Description

1-(2-Bromoethyl)-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a reactive bromoethyl side chain and a fluorinated aromatic ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorobenzene moiety linked via an ethyl spacer for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromoethyl group.
• Ligand & Catalyst Development: Utilized in organic and organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers to introduce fluorine-containing side chains, altering material properties.

Basic Information

Product Name	1-(2-Bromoethyl)-4-Fluorobenzene
CAS No.	332-42-3
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	2-(4-Fluorophenyl)ethyl Bromide; 4-Fluorophenethyl Bromide; (4-Fluorophenyl)ethyl Bromide; 1-Bromo-2-(4-fluorophenyl)ethane; 2-Bromo-1-(4-fluorophenyl)ethane; p-Fluorophenethyl Bromide; β-Bromo-4-fluoroethylbenzene; 4-Fluoro-β-bromoethylbenzene
EINECS	206-375-5

Quality Control

Our 1-(2-Bromoethyl)-4-Fluorobenzene is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.520 - 1.525
Density (20°C)	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.