Description

3-Chloro-4-(Trifluoromethyl)Benzoyl Fluoride is a high-value, multi-functional aromatic building block characterized by its reactive benzoyl fluoride and trifluoromethyl groups. This compound matters for its critical role in the synthesis of advanced agrochemicals and pharmaceuticals, where it serves as a key precursor for introducing the 3-chloro-4-(trifluoromethyl)benzoyl moiety. Chemical manufacturers and R&D laboratories in the agrochemical, pharmaceutical, and specialty chemical sectors need this intermediate to develop new active ingredients and functional materials.

Application

• Agrochemical Intermediate: A crucial precursor for synthesizing herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and chloro substituents.
• Pharmaceutical Building Block: Used in medicinal chemistry to construct complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating advanced functional materials used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed to introduce specific aromatic and fluorinated groups into polymer chains, altering material properties like chemical resistance and thermal stability.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl structures.
• Fluorination Reagent Precursor: The benzoyl fluoride group can be utilized or transformed to introduce fluorine atoms into target molecules.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethyl)Benzoyl Fluoride
CAS No.	320-62-7
Molecular Formula	C8H3ClF4O
Molecular Weight	226.56 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)benzoyl fluoride; 3-Chloro-alpha,alpha,α-trifluoro-p-toluoyl fluoride; 2-Chloro-alpha,alpha,α-trifluoro-p-toluoyl fluoride; Benzoyl fluoride, 3-chloro-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-3-chlorobenzoyl fluoride; 3-Chloro-4-trifluoromethylbenzoyl fluoride; p-Toluoyl fluoride, 3-chloro-alpha,alpha,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Trifluoromethyl)Benzoyl Fluoride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.