Description

Orotidine CAS NO 314-50-1 is a pyrimidine nucleoside derivative, serving as a key intermediate in the biosynthesis of uridine monophosphate (UMP) within the *de novo* pyrimidine pathway. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in nucleotide metabolism. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers for applications in enzymology studies, metabolic pathway analysis, and as a reference standard.

Application

• Biochemical Research: Used as a critical substrate and intermediate in studies of the *de novo* pyrimidine biosynthesis pathway and related enzymatic reactions.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in drug discovery and manufacturing.
• Enzymology Studies: Employed in assays to study the activity and kinetics of enzymes like orotidine-5'-phosphate decarboxylase (OMP decarboxylase).
• Metabolic Disorder Research: Investigated in research related to inborn errors of metabolism, such as orotic aciduria.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of diagnostic kits for assessing pyrimidine metabolism.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in biochemistry, molecular biology, and cell biology.

Basic Information

Product Name	Orotidine
CAS No.	314-50-1
Molecular Formula	C10H12N2O8
Molecular Weight	288.21 g/mol
Synonyms	6-Carboxyuridine; Orotic acid riboside; 1-β-D-Ribofuranosylorotic acid; Uridine-6-carboxylic acid; NSC 52904; 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid β-D-ribofuranosyl ester
EINECS	206-254-9

Quality Control

Our Orotidine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.