Description

Desmosterol is a key intermediate sterol in the cholesterol biosynthesis pathway, specifically the immediate precursor to cholesterol. This compound is of significant interest in biochemical and pharmaceutical research for studying lipid metabolism and enzyme inhibition. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers focused on metabolic disorders, cardiovascular health, and cholesterol-lowering drug mechanisms.

Application

• Biochemical Research: Critical intermediate for studying the final step of cholesterol biosynthesis catalyzed by the enzyme 24-dehydrocholesterol reductase.
• Pharmaceutical Development: Used as a reference standard and starting material in the research and development of novel lipid-regulating therapeutics.
• Diagnostic Assays: Serves as a calibrant or control in analytical methods (e.g., GC-MS, LC-MS) for quantifying sterol profiles in clinical and research laboratories.
• Enzyme Inhibition Studies: Essential for investigating the mechanism of action of drugs that target the cholesterol synthesis pathway, such as certain statins.
• Cell Culture & Metabolism: Used in in vitro studies to understand cellular cholesterol homeostasis and trafficking.
• Nutritional Science: Employed in research examining dietary impacts on endogenous cholesterol synthesis and absorption.

Basic Information

Product Name	Desmosterol
CAS No.	313-04-2
Molecular Formula	C27H44O
Molecular Weight	384.64 g/mol
Synonyms	24-Dehydrocholesterol; (3β)-Cholesta-5,24-dien-3-ol; δ5,24-Cholestadien-3β-ol; 5,24-Cholestadien-3β-ol; Desmosterin; 3β-Hydroxycholesta-5,24-diene
EINECS	206-224-9

Quality Control

Our Desmosterol is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in your analytical and experimental workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.