Description

Dl-Thyroxine CAS NO 300-30-1 is a synthetic thyroid hormone analog, chemically known as 3,5,3',5'-Tetraiodo-DL-thyronine. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying thyroid hormone activity and metabolism. It is essential for manufacturers and research institutions focused on endocrinology, metabolic disorder therapeutics, and analytical method development.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) in quality control laboratories.
• Biochemical Research: Serves as a key reagent in studies investigating thyroid hormone receptor binding, metabolic pathways, and hormone synthesis mechanisms.
• Active Pharmaceutical Ingredient (API) Intermediate: An important synthetic precursor in the production of thyroid hormone medications and related analogs.
• Diagnostic Kit Development: Utilized in the formulation of calibration solutions and controls for immunoassays and clinical diagnostic tests measuring thyroid function.
• Metabolic Studies: Applied in preclinical research to model and understand the effects of thyroid hormones on metabolism, growth, and development.

Basic Information

Product Name	Dl-Thyroxine
CAS No.	300-30-1
Molecular Formula	C15H11I4NO4
Molecular Weight	776.87 g/mol
Synonyms	DL-Thyroxine; DL-T4; (±)-Thyroxine; 3,5,3',5'-Tetraiodo-DL-thyronine; Thyroxine DL-; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-DL-tyrosine; Levothyroxine impurity; Thyroxine racemic mixture
EINECS	206-079-1

Quality Control

Our Dl-Thyroxine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include results from advanced techniques like HPLC and spectroscopic analysis. Specifications are designed to meet the stringent requirements of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.