Description

C-Di-Amp Disodium is a high-purity, specialized nucleotide analog used as a critical building block in oligonucleotide synthesis. This compound matters for its role in the development of advanced therapeutic and diagnostic agents, including antisense oligonucleotides and aptamers. It is essential for pharmaceutical R&D, biotechnology companies, and diagnostic manufacturers requiring precise and reliable synthetic intermediates for nucleic acid-based applications.

Application

• Oligonucleotide Synthesis: A key phosphoramidite monomer for the solid-phase synthesis of DNA and RNA strands.
• Therapeutic Development: Used in the research and production of antisense oligonucleotides (ASOs) and siRNA for targeted gene silencing therapies.
• Diagnostic Probes: Serves as a component in the manufacture of labeled probes and primers for PCR, sequencing, and molecular diagnostics.
• Aptamer Production: Integral to the synthesis of chemically modified aptamers with enhanced stability and binding affinity.
• Research Reagents: Provides a high-quality standard for academic and industrial research in molecular biology and biochemistry.
• Next-Generation Sequencing (NGS): Can be utilized in the preparation of specialized nucleotide libraries for advanced genomic studies.

Basic Information

Product Name	C-Di-Amp Disodium
CAS No.	2734909-87-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic di-AMP disodium salt; 3',5'-Cyclic diadenylic acid disodium; c-di-AMP Na2; Cyclic diadenosine monophosphate disodium; CDAS; Cyclic Dinucleotide Disodium Salt; c-di-AMP (Disodium)
EINECS	Contact for details

Quality Control

Our C-Di-Amp Disodium is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to support regulatory filings for drug substance intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.