Description

Blu-945 is a high-purity, advanced pharmaceutical intermediate or active ingredient identified by CAS No. 2660250-10-0. This compound is critical for research and development in targeted oncology therapies, offering a precise chemical tool for investigating novel treatment pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and academic research institutions focused on next-generation cancer treatments and biochemical mechanism studies.

Application

• Oncology Drug Discovery: Serves as a key intermediate or reference standard in the synthesis and development of novel targeted cancer therapeutics.
• Biochemical Research: Used as a selective inhibitor or modulator in enzymatic and cellular pathway studies to understand disease mechanisms.
• Preclinical Development: Employed in in vitro and in vivo studies to evaluate pharmacokinetics, efficacy, and safety profiles of new drug candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Blu-945
CAS No.	2660250-10-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BLU-945; 2660250-10-0; UNII-8HXK8T4Y4I; CHEMBL4827005; BDBM50388857; AKOS040759623; (2E)-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2-[(3S)-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)pyrrolidin-1-yl]pyrimidine-5-carboxamide
EINECS	Contact for details

Quality Control

Our Blu-945 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity determination by chromatographic techniques (HPLC). A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.