Description

3’-Deoxy-2’,5’-Di-o-Acetyl-8-Hydroxyguanosine is a chemically modified nucleoside derivative, serving as a crucial intermediate in advanced pharmaceutical research and synthesis. This compound is valued for its role in the development of novel antiviral and anticancer therapeutics, particularly in the synthesis of nucleotide analogs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of experimental antiviral and anticancer nucleotide prodrugs.
• Biochemical Research: Used in studies investigating nucleoside metabolism, enzyme inhibition, and mechanism of action.
• Prodrug Development: Serves as a protected precursor for developing more bioavailable or targeted nucleoside therapeutics.
• Antiviral Agent Synthesis: Intermediate in the research and development pipeline for novel antiviral compounds.
• Reference Standard: Employed as an analytical standard in quality control and method development for nucleoside-based APIs.
• Organic Synthesis: Valuable synthon in complex organic transformations requiring protected nucleoside scaffolds.

Basic Information

Product Name	3’-Deoxy-2’,5’-Di-o-Acetyl-8-Hydroxyguanosine
CAS No.	2389988-72-9
Molecular Formula	C₁₄H₁₇N₅O₇
Molecular Weight	367.32 g/mol
Synonyms	8-Hydroxy-2',5'-di-O-acetyl-3'-deoxyguanosine; 3'-Deoxy-2',5'-di-O-acetyl-8-hydroxyguanosine; 8-Hydroxy-3'-deoxy-2',5'-di-O-acetylguanosine; 8-OH-dG Diacetate; 2',5'-Di-O-acetyl-3'-deoxy-8-hydroxyguanosine; 8-Hydroxy-2',5'-diacetyl-3'-deoxyguanosine; Guanosine, 3'-deoxy-2',5'-di-O-acetyl-8-hydroxy-
EINECS	Contact for details

Quality Control

Our 3’-Deoxy-2’,5’-Di-o-Acetyl-8-Hydroxyguanosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.