Description

2'-Deoxy-2'-Fluoro-N1-Methyl Inosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of next-generation nucleotide-based drugs. The precise structural modifications offer unique mechanisms of action, making it a critical component for targeted therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of modified oligonucleotides and nucleotide analogs for therapeutic use.
• Antiviral Drug Research: Investigated for incorporation into prodrugs targeting RNA viruses, leveraging its modified sugar moiety to inhibit viral replication.
• Oncology Research: Used in the development of chemotherapeutic agents designed to disrupt cancer cell proliferation at the genetic level.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Prodrug Development: Acts as a precursor molecule in creating more bioavailable and targeted prodrug formulations.
• Diagnostic Probe Synthesis: Utilized in creating labeled nucleotides for diagnostic assays and imaging techniques.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-N1-Methyl Inosine
CAS No.	2376610-64-7
Molecular Formula	C11H13FN4O5
Molecular Weight	300.24 g/mol
Synonyms	1-Methyl-2'-deoxy-2'-fluoroinosine; N1-Methyl-2'-deoxy-2'-fluoroinosine; 2'-Fluoro-2'-deoxy-N1-methylinosine; 9-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methyl-6,9-dihydro-1H-purin-6-one; 2'-F-N1-Me-Inosine; 2'-F-1-Me-Ino; 2'-Deoxy-2'-fluoro-1-methylinosine
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-N1-Methyl Inosine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to maintain stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.