Description

5-Azacytosine Dipentose is a nucleoside analog derivative of cytosine, where a nitrogen atom replaces the carbon at the 5-position of the pyrimidine ring, conjugated with a dipentose sugar moiety. This structural modification is significant for its role as a potent epigenetic modulator and metabolic inhibitor, primarily affecting nucleic acid synthesis and function. It is a critical building block and research chemical for pharmaceutical development, particularly in the fields of oncology and virology, where it is used to study DNA methylation and develop novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nucleoside-based anticancer and antiviral agents.
• Biochemical Research: Used as a tool compound in epigenetic studies to investigate DNA methylation patterns and gene silencing mechanisms.
• Antimetabolite Development: Acts as a base for developing compounds that interfere with cellular metabolism, particularly in rapidly dividing cells.
• Virology Studies: Employed in research for designing nucleoside analogs that target viral polymerases.
• Oncology Research: Utilized in preclinical studies to evaluate the efficacy of new chemotherapeutic strategies involving DNA incorporation and disruption.
• Enzyme Inhibition Studies: Applied in assays to study the inhibition of enzymes like DNA methyltransferases (DNMTs).

Basic Information

Product Name	5-Azacytosine Dipentose
CAS No.	2306050-23-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-Azacytidine dipentose; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2-dihydro-4-amino-1,3,5-triazin-2-one (deprotected sugar form); Azacitidine dipentose derivative; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one (dipentose); NSC related analog; Ladakamycin precursor; 5-Aza-2'-deoxycytidine related compound; Epigenetic modulator intermediate
EINECS	Contact for details

Quality Control

Our 5-Azacytosine Dipentose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.