Description

N1,N2-Dimethyl-2'-o-Methylguanosine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This high-purity compound is essential for developing novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in oligonucleotide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified mRNA and oligonucleotide-based therapeutics.
• Antiviral Drug Research: Used in the development of nucleoside analogs targeting viral polymerases.
• Oncology Research: Serves as a building block for creating novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate RNA modification pathways and function.
• Academic & Contract Research: Utilized in university laboratories and CROs for fundamental research in nucleic acid chemistry and epigenetics.
• Diagnostic Probe Development: Incorporated into probes for detecting specific RNA sequences or studying RNA-protein interactions.

Basic Information

Product Name	N1,N2-Dimethyl-2'-o-Methylguanosine
CAS No.	2305416-05-9
Molecular Formula	C13H19N5O5
Molecular Weight	325.32 g/mol
Synonyms	2'-O-Methyl-N1,N2-dimethylguanosine; N1,N2-Dimethyl-2'-O-methylguanosine; 1,2-Dimethyl-2'-O-methylguanosine; 2'-OMe-N1,N2-dimethylguanosine; Modified Guanosine Derivative; DMG-2'-OMe; CAS 2305416-05-9
EINECS	Contact for details

Quality Control

Our N1,N2-Dimethyl-2'-o-Methylguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.