Description

5'-Deoxy-5'-n-(2-Bromoethyl)Amino Thymidine is a high-purity, modified nucleoside derivative designed for advanced research and pharmaceutical development. This compound serves as a critical building block and alkylating agent in the synthesis of novel oligonucleotide conjugates and targeted therapeutics. It is essential for scientists and manufacturers in the fields of nucleic acid chemistry, medicinal chemistry, and bioconjugation, enabling the creation of probes, drug delivery systems, and next-generation antiviral or anticancer agents.

Application

• Oligonucleotide Synthesis: Key intermediate for the site-specific functionalization and labeling of DNA/RNA strands.
• Bioconjugation & Linker Chemistry: Used to attach therapeutic payloads, fluorophores, or other functional groups to biomolecules via its reactive bromoethylamino moiety.
• Antiviral & Anticancer Prodrug Development: Serves as a precursor in the design of nucleoside analog prodrugs for targeted therapy.
• Chemical Biology Research: Employed in the study of nucleic acid interactions, enzyme mechanisms, and cellular processes.
• Diagnostic Probe Manufacture: Utilized in creating sensitive and specific detection probes for diagnostic assays.

Basic Information

Item	Detail
Product Name	5'-Deoxy-5'-n-(2-Bromoethyl)Amino Thymidine
CAS No.	2305415-99-8
Molecular Formula	C12H18BrN3O5
Molecular Weight	364.19 g/mol
Synonyms	5'-Deoxy-5'-(2-bromoethylamino)thymidine; 2'-Deoxythymidine, 5'-deoxy-5'-[(2-bromoethyl)amino]-; 5'-Amino-5'-deoxythymidine, N-(2-bromoethyl) derivative; BrEA-dT; (2-Bromoethyl)amino-thymidine derivative; 5'-Deoxy-5'-N-(2-bromoethyl)aminothymidine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-n-(2-Bromoethyl)Amino Thymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.