Description

3-Deaza-4'-C-Methyluridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is specifically engineered to study and modulate RNA function, offering unique properties for probing nucleic acid structure and metabolism. It is primarily utilized by research scientists and development teams in the pharmaceutical, biotechnology, and academic sectors for applications in antiviral drug discovery, oligonucleotide synthesis, and molecular biology.

Application

• Antiviral Drug Discovery: Serves as a critical intermediate or active pharmaceutical ingredient (API) in the development of novel antiviral therapeutics targeting RNA viruses.
• Oligonucleotide Synthesis: Used as a modified phosphoramidite or solid-support reagent for the synthesis of non-natural oligonucleotides with enhanced stability or specific binding properties.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to investigate the mechanisms of nucleoside-metabolizing enzymes and RNA polymerases.
• Molecular Probe Development: Incorporated into probes for studying RNA structure, function, and localization within cellular systems.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of nucleoside-based candidates.

Basic Information

Product Name	3-Deaza-4'-C-Methyluridine
CAS No.	2305415-96-5
Molecular Formula	C11H15N3O6
Molecular Weight	285.25 g/mol
Synonyms	4'-C-Methyl-3-deazauridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-4-methyl-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2-dihydropyrimidine-2,4-dione; 3-Deaza-4'-C-methyluridine; 4'-Methyl-3-deazauridine; Modified Uridine Derivative; Nucleoside Analog
EINECS	Contact for details

Quality Control

Our 3-Deaza-4'-C-Methyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.