Description

5'-Deoxy-5'-N,n-Diethylamino Thymidine is a modified nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral agents, oligonucleotides, and other therapeutic molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, specialized nucleoside analogs for drug discovery and development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used in the research and development of modified antisense oligonucleotides and siRNA.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Diagnostic Probe Development: Employed in the creation of labeled nucleosides for diagnostic assays and imaging.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Academic & Institutional Research: Fundamental material for studies in nucleic acid chemistry and molecular biology.

Basic Information

Product Name	5'-Deoxy-5'-N,n-Diethylamino Thymidine
CAS No.	2305415-88-5
Molecular Formula	C14H23N3O5
Molecular Weight	313.35 g/mol
Synonyms	5'-Deoxy-5'-(N,N-diethylamino)thymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-[(diethylamino)methyl]tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 5'-N,N-Diethylamino-5'-deoxythymidine; Thymidine, 5'-deoxy-5'-(N,N-diethylamino)-; 5'-Deoxy-5'-diethylaminothymidine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-N,n-Diethylamino Thymidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.