Description

5'(R)-C-Methyl-3-Deazauridine is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs targeting RNA viruses and specific oncological pathways. The product is supplied under stringent quality control to ensure consistency and reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research-scale synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA metabolism and related biological pathways.
• Antiviral Agent Development: Serves as a core structural component for developing therapeutics against RNA viruses.
• Oncology Research: Employed in the discovery of compounds that interfere with nucleotide synthesis in rapidly dividing cells.
• Chemical Biology Probes: Utilized to create labeled or modified probes for studying cellular processes and target engagement.
• Process Chemistry: Acts as a starting material for process development and scale-up activities in active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	5'(R)-C-Methyl-3-Deazauridine
CAS No.	2305415-82-9
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5'-C-Methyl-3-deazauridine (R-isomer); (5'R)-5'-C-Methyl-3-deazauridine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1,2-dihydropyrimidin-4-one; 3-Deaza-5'-C-methyluridine; Modified Nucleoside Intermediate; Research Grade Nucleoside Analog
EINECS	Contact for details

Quality Control

Every batch of 5'(R)-C-Methyl-3-Deazauridine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.