Description

N6-(3-Trifluoromethylbenzyl)-3'-Deoxyadenosine is a synthetic nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways, particularly in oncology and virology. It is primarily needed by research institutions, biotechnology firms, and pharmaceutical companies engaged in the synthesis of nucleotide-based drugs and high-value biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand adenosine-related metabolic pathways.
• Proteomics & Molecular Biology: Acts as a tool compound for studying protein-nucleic acid interactions and signal transduction mechanisms.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Preclinical Development: Employed in the development and testing of new therapeutic candidates targeting DNA/RNA synthesis.

Basic Information

Product Name	N6-(3-Trifluoromethylbenzyl)-3'-Deoxyadenosine
CAS No.	2305415-80-7
Molecular Formula	C18H18F3N5O3
Molecular Weight	409.36 g/mol
Synonyms	3'-Deoxy-N6-[(3-trifluoromethyl)benzyl]adenosine; 3'-Deoxy-N6-(3-(trifluoromethyl)benzyl)adenosine; N6-(3-Trifluoromethylbenzyl)-3'-deoxyadenosine; 1-(6-Amino-9H-purin-9-yl)-1,3-dideoxy-3-[3-(trifluoromethyl)benzyl]amino-β-D-ribofuranose; Adenosine, N6-[(3-trifluoromethyl)phenyl]methyl-3'-deoxy-; 2305415-80-7
EINECS	Contact for details

Quality Control

Our N6-(3-Trifluoromethylbenzyl)-3'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. The compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.