Description

4'-C-Methyl-5-Methoxyuridine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block for the synthesis of novel oligonucleotides and therapeutic agents, offering unique structural properties for modulating biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the development of next-generation antiviral drugs, mRNA therapeutics, and diagnostic probes. The compound is supplied with a CAS Number of 2305415-71-6.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used as a modified monomer for incorporating specific functionalities into DNA/RNA strands for research and therapeutic applications.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms, nucleic acid metabolism, and structure-activity relationships (SAR).
• Pro-drug Development: Employed in the design and synthesis of pro-drugs to enhance the bioavailability and targeting of active pharmaceutical ingredients (APIs).
• Diagnostic Probe Synthesis: Utilized in creating labeled nucleotides for use in diagnostic assays and imaging techniques.
• Academic & Industrial R&D: Fundamental research in medicinal chemistry, chemical biology, and nucleic acid technology.

Basic Information

Product Name	4'-C-Methyl-5-Methoxyuridine
CAS No.	2305415-71-6
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	5-Methoxy-4'-C-methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 4'-C-Methyl-5-methoxy-1-((2R,3R,4S,5R)-3,4,5-trihydroxy-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Modified Uridine Derivative; 4'-C-Methyl-5-Methoxy-Uridine
EINECS	Contact for details

Quality Control

Our 4'-C-Methyl-5-Methoxyuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.