Description

Benzo[D][1,3]Dioxole-5-Carbonyl Fluoride is a high-value, reactive fluorinated building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the 1,3-benzodioxole moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive carbonyl fluoride group for selective coupling.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Fluorination Reagent: Acts as a source of the carbonyl fluoride group for introducing fluorinated segments into complex organic molecules under controlled conditions.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and the creation of targeted molecular libraries.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying enzyme activity and biological pathways.

Basic Information

Product Name	Benzo[D][1,3]Dioxole-5-Carbonyl Fluoride
CAS No.	2254447-02-2
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	1,3-Benzodioxole-5-carbonyl fluoride; 5-(Fluoroformyl)-1,3-benzodioxole; Piperonyloyl fluoride; 3,4-(Methylenedioxy)benzoyl fluoride; 3,4-Methylenedioxybenzoyl fluoride; 1,3-Benzodioxol-5-ylcarbonyl fluoride; 5-Carboxy-1,3-benzodioxole fluoride
EINECS	Contact for details

Quality Control

Our Benzo[D][1,3]Dioxole-5-Carbonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.