Description

Azido-Peg11-Alcohol is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive azide group at one terminus and a hydroxyl group at the other. This unique structure makes it an invaluable cross-linking and spacer molecule for bioconjugation and materials science, enabling the creation of stable triazole linkages via click chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotech, and advanced materials sectors for developing drug delivery systems, functionalized surfaces, and hydrogel networks.

Application

• Bioconjugation and ADC Development: Used as a hydrophilic linker to conjugate cytotoxic drugs to antibodies (Antibody-Drug Conjugates) or other targeting molecules, improving solubility and pharmacokinetics.
• Surface Functionalization: Employed to modify nanoparticles, biosensors, and diagnostic chips with azide groups for subsequent click chemistry-based attachment of biomolecules.
• Polymer and Hydrogel Synthesis: Acts as a cross-linker or co-monomer in the preparation of PEG-based hydrogels and smart materials for tissue engineering and controlled release applications.
• Peptide and Protein Modification: Facilitates site-specific labeling or PEGylation of peptides and proteins to enhance stability, reduce immunogenicity, or attach probes.
• Lipid and Micelle Functionalization: Incorporated into lipid formulations or polymeric micelles to introduce azide handles for targeted drug delivery system assembly.
• Diagnostic Reagent Preparation: Serves as a key intermediate in synthesizing fluorescent or other detection probes for assays and imaging.

Basic Information

Product Name	Azido-Peg11-Alcohol
CAS No.	2252392-53-1
Molecular Formula	C26H53N3O12
Molecular Weight	599.71 g/mol
Synonyms	11-Azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-ol; Azido-PEG11-OH; N3-PEG11-OH; α-Azido-ω-hydroxy-undecaethylene glycol; PEG11 Azide Alcohol; Azido-Polyethylene Glycol11-Alcohol; 1-Azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-35-ol
EINECS	Contact for details

Quality Control

Our Azido-Peg11-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent molecular weight, and functional group integrity. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment supports applications requiring reproducible and reliable performance in sensitive research and GMP-grade manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight (GPC/NMR)	Conforms (approx. 600 Da)
Functional Group Assay (Azide)	≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.