Description

1,4-Benzenedicarboxaldehyde, 2,5-Bis[2-(2-Azidoethoxy)Ethoxy]- is a specialized bifunctional aromatic dialdehyde derivative, engineered with azide-terminated polyether side chains. This compound is a critical high-purity building block for advanced material synthesis, offering orthogonal reactivity for click chemistry and polymer cross-linking applications. It is essential for R&D and production in the pharmaceutical, advanced polymer, and specialty chemical industries where precise molecular architecture is required.

Application

• Click Chemistry Reagent: Serves as a key precursor for Huisgen 1,3-dipolar cycloaddition reactions, enabling the synthesis of complex triazole-linked dendrimers, polymers, and bioconjugates.
• Polymer Cross-linking Agent: Used to create highly cross-linked, functional polymer networks and hydrogels with tunable properties for medical devices and controlled release systems.
• Pharmaceutical Intermediate: Employed in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs that require precise, bio-orthogonal linkage strategies.
• Surface Functionalization: Facilitates the covalent attachment of functional layers to surfaces (e.g., nanoparticles, chips, sensors) via its reactive aldehyde and azide groups.
• Material Science Research: A vital component in developing new smart materials, self-healing polymers, and shape-memory alloys through its dual functionality.
• Ligand and Probe Synthesis: Used to construct multifunctional ligands for catalysis or fluorescent probes for bioimaging and diagnostics.

Basic Information

Product Name	1,4-Benzenedicarboxaldehyde, 2,5-Bis[2-(2-Azidoethoxy)Ethoxy]-
CAS No.	2245262-44-4
Molecular Formula	C20H26N6O8
Molecular Weight	478.46 g/mol
Synonyms	2,5-Bis[2-(2-azidoethoxy)ethoxy]terephthalaldehyde; Terephthalaldehyde, 2,5-bis[2-(2-azidoethoxy)ethoxy]-; Bifunctional Azido-PEG Terephthalaldehyde; Azide-PEG Dialdehyde Crosslinker; 2,5-Bis(2-(2-azidoethoxy)ethoxy)-1,4-benzenedicarboxaldehyde; Click Chemistry Dialdehyde; Dual-Functional Aromatic Azide Aldehyde
EINECS	Contact for details

Quality Control

Every batch of 1,4-Benzenedicarboxaldehyde, 2,5-Bis[2-(2-Azidoethoxy)Ethoxy]- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and FT-IR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Keep away from heat, sparks, open flames, and incompatible materials. This material is light-sensitive and easily oxidized.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.