Description

Azidoethyl-Ss-Propionic Acid is a specialized bifunctional organic compound featuring both an azide group and a carboxylic acid moiety. This unique structure makes it a valuable click chemistry reagent and a versatile bifunctional linker for the synthesis of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for constructing novel drug candidates, functional polymers, and diagnostic probes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs via azide-alkyne cycloaddition (CuAAC) reactions.
• Bioconjugation & Probe Development: Used to label proteins, antibodies, and oligonucleotides for creating targeted imaging agents, antibody-drug conjugates (ADCs), and diagnostic assays.
• Polymer & Materials Science: Acts as a functional monomer or cross-linker for introducing reactive azide groups into polymers, hydrogels, and surface coatings to enable further chemical modification.
• Chemical Biology Research: A crucial tool for studying biological processes through bioorthogonal labeling strategies in live cells and organisms.
• Peptide & Protein Modification: Facilitates site-specific modification of peptides and proteins to alter their properties or attach payloads.

Basic Information

Item	Detail
Product Name	Azidoethyl-Ss-Propionic Acid
CAS No.	2228857-32-5
Molecular Formula	C5H9N3O2S2
Molecular Weight	207.27 g/mol
Synonyms	3-(2-Azidoethylsulfanyl)propanoic Acid; 2-(2-Azidoethylthio)acetic Acid (common misnomer); Azido-PEG2-thioacetic Acid; S-(2-Azidoethyl) 3-mercaptopropionate derivative; Azidoethylthiopropionic Acid; AETPA; Click Chemistry Linker with Acid; Bifunctional Azido-Acid Linker
EINECS	Contact for details

Quality Control

Our Azidoethyl-Ss-Propionic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.