Description

Kras G12C Inhibitor 3 is a potent and selective small molecule inhibitor designed to target the KRAS G12C mutant protein, a key oncogenic driver in various cancers. This high-purity compound is critical for advancing oncology research and the development of targeted cancer therapies. It is an essential research chemical for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on precision medicine and drug discovery for non-small cell lung cancer (NSCLC), colorectal cancer, and pancreatic cancer.

Application

• Biochemical Research: Used as a reference standard and active pharmaceutical ingredient (API) in studies investigating KRAS G12C signaling pathways and mutant protein inhibition mechanisms.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis and optimization of next-generation targeted cancer therapeutics.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate the efficacy, pharmacokinetics, and pharmacodynamics of KRAS G12C-targeted treatments.
• High-Throughput Screening (HTS): Utilized as a control compound in assays designed to identify novel inhibitors or combination therapies.
• Mechanism of Action (MOA) Studies: Essential for elucidating the structural and functional interactions between the inhibitor and the KRAS G12C mutant protein.

Basic Information

Product Name	Kras G12C Inhibitor 3
CAS No.	2206735-75-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	KRAS G12C Inhibitor 3; G12C Inhibitor 3; Compound 2206735-75-1; KRAS(G12C) inhibitor; Oncogenic KRAS inhibitor; Targeted cancer therapy inhibitor; Mutant KRAS inhibitor
EINECS	Contact for details

Quality Control

Our Kras G12C Inhibitor 3 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency required for sensitive research applications. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.