Description

Hs-Peg11-Ch2Ch2N3 CAS NO 2148986-08-5 is a heterobifunctional polyethylene glycol (PEG) linker featuring a hydroxyl group and an azide terminus. This specialized chemical is engineered to facilitate controlled bioconjugation and cross-linking in advanced material science and pharmaceutical development. It is an essential reagent for researchers and manufacturers in the fields of biopharmaceuticals, diagnostics, and polymer chemistry who require precise and stable molecular assembly.

Application

• Bioconjugation and ADC Development: Used as a linker for attaching cytotoxic drugs to antibodies in Antibody-Drug Conjugate (ADC) therapeutics.
• PEGylation Reagent: Serves to modify peptides, proteins, and oligonucleotides to enhance solubility, stability, and circulation half-life.
• Click Chemistry: The terminal azide group enables efficient, site-specific conjugation via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
• Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent to create biocompatible hydrogels for drug delivery systems and tissue engineering scaffolds.
• Surface Functionalization: Utilized to modify nanoparticles, biosensors, and diagnostic assay surfaces with functional groups for further coupling.
• Polymer Chemistry: A key building block for synthesizing block copolymers and functionalized polymeric materials with tailored properties.

Basic Information

Product Name	Hs-Peg11-Ch2Ch2N3
CAS No.	2148986-08-5
Molecular Formula	C27H55N3O13
Molecular Weight	629.75 g/mol
Synonyms	11-Azido-3,6,9-trioxaundecan-1-ol; Heterobifunctional PEG Azide; α-Hydroxy-ω-azido PEG; Azido-PEG11-alcohol; N3-PEG11-OH; PEG11 Azide Hydroxy; HS-PEG11-N3; 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
EINECS	Contact for details

Quality Control

Our Hs-Peg11-Ch2Ch2N3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and moisture absorption. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize condensation and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Molecular Weight Confirmation (MS)	Conforms
Functional Group Assay (Azide)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.