Description

2-(5-Fluoro-2-Hydroxyphenyl)-2-(1-Oxo-6-(4-(Piperazin-1-Yl)Phenyl)Isoindolin-2-Yl)-n-(Thiazol-2-Yl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. Its complex molecular architecture, featuring a fused isoindolinone core linked to fluorinated and heterocyclic moieties, makes it a critical building block for targeted drug discovery. This compound is essential for research and development teams in the pharmaceutical and biotechnology sectors, particularly those focused on oncology, CNS disorders, and other areas requiring sophisticated small-molecule candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs) with potential kinase inhibitory or receptor-modulating activity.
• Drug Discovery & Medicinal Chemistry: Serves as a core scaffold for constructing compound libraries aimed at high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Research: Used in the development of targeted cancer therapies, leveraging its structural features for potential interaction with specific biological pathways.
• Biochemical Research: Employed as a tool compound or a labeled analog in proteomics and molecular biology research to study disease mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and pharmacology projects.

Basic Information

Product Name	2-(5-Fluoro-2-Hydroxyphenyl)-2-(1-Oxo-6-(4-(Piperazin-1-Yl)Phenyl)Isoindolin-2-Yl)-n-(Thiazol-2-Yl)Acetamide
CAS No.	2140807-05-0
Molecular Formula	C29H25FN6O3S
Molecular Weight	556.62 g/mol
Synonyms	2-(5-Fluoro-2-hydroxyphenyl)-2-[1-oxo-6-[4-(piperazin-1-yl)phenyl]isoindolin-2-yl]-N-1,3-thiazol-2-ylacetamide; 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide; UNII-7K8J1X8V4N; 7K8J1X8V4N; Acetamide, 2-(5-fluoro-2-hydroxyphenyl)-2-[1-oxo-6-[4-(1-piperazinyl)phenyl]-2-isoindolinyl]-N-2-thiazolyl-; CAS 2140807-05-0
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-2-Hydroxyphenyl)-2-(1-Oxo-6-(4-(Piperazin-1-Yl)Phenyl)Isoindolin-2-Yl)-n-(Thiazol-2-Yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.