Description

(2,5-Difluoro-4-Isopropoxyphenyl)Methanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the isopropoxy group, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the difluoro motif can enhance biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: The benzylic alcohol and halogenated aromatic structure make it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorine chemistry and novel heterocyclic systems.

Basic Information

Product Name	(2,5-Difluoro-4-Isopropoxyphenyl)Methanol
CAS No.	2121514-71-2
Molecular Formula	C10H12F2O2
Molecular Weight	202.20 g/mol
Synonyms	2,5-Difluoro-4-isopropoxybenzyl alcohol; 4-(Isopropoxy)-2,5-difluorobenzyl alcohol; (4-Isopropoxy-2,5-difluorophenyl)methanol; 1-(2,5-Difluoro-4-isopropoxyphenyl)methanol; α-Hydroxymethyl-2,5-difluoro-4-isopropoxybenzene; Benzyl alcohol, 2,5-difluoro-4-(1-methylethoxy)-
EINECS	Contact for details

Quality Control

Our (2,5-Difluoro-4-Isopropoxyphenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.