Description

2-{3-Bromobicyclo[1.1.1]Pentan-1-Yl}-1-Phenylethan-1-One is a high-value, advanced pharmaceutical intermediate featuring a unique strained bicyclo[1.1.1]pentane (BCP) scaffold. This compound is specifically engineered to serve as a key building block in modern drug discovery, enabling the synthesis of novel bioactive molecules with improved metabolic stability and physicochemical properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly for challenging targets in oncology and CNS diseases.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting protein-protein interactions.
• Bioisostere Development: Used to incorporate the rigid, three-dimensional bicyclo[1.1.1]pentane moiety as a bioisostere for aromatic rings or tert-butyl groups to optimize drug properties like solubility and metabolic stability.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Potential application in the development of new-generation pesticides and herbicides with novel modes of action.
• Material Science Precursor: Can be utilized in the synthesis of specialized monomers for advanced polymers with unique structural characteristics.

Basic Information

Product Name	2-{3-Bromobicyclo[1.1.1]Pentan-1-Yl}-1-Phenylethan-1-One
CAS No.	2102408-90-0
Molecular Formula	C13H13BrO
Molecular Weight	265.15 g/mol
Synonyms	2-(3-Bromobicyclo[1.1.1]pentan-1-yl)-1-phenylethan-1-one; 1-Phenylethanone, 2-(3-bromobicyclo[1.1.1]pent-1-yl)-; 3-Bromo-1-(2-oxo-2-phenylethyl)bicyclo[1.1.1]pentane; BCP-Br Phenylethanone Derivative; (3-Bromobicyclo[1.1.1]pentan-1-yl)(phenyl)methanone precursor
EINECS	Contact for details

Quality Control

Our 2-{3-Bromobicyclo[1.1.1]Pentan-1-Yl}-1-Phenylethan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.