Description

n-[2-[2-(Dimethylamino)Ethyl(Methyl)Amino]-5-[[4-(1H-Indol-3-Yl)Thieno[3,2-D]Pyrimidin-2-Yl]Amino]-4-Methoxyphenyl]Prop-2-Enamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in targeted cancer therapies, particularly as a key building block for kinase inhibitors. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the synthesis of novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel kinase inhibitor candidates for oncology research.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic and cellular assays to study specific biological pathways.
• Preclinical Development: Serves as a starting material or intermediate for scale-up studies and formulation development of potential drug substances.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery.
• Custom Synthesis: Supplied to partners for the development of proprietary compounds and new chemical entities (NCEs).

Basic Information

Item	Detail
Product Name	n-[2-[2-(Dimethylamino)Ethyl(Methyl)Amino]-5-[[4-(1H-Indol-3-Yl)Thieno[3,2-D]Pyrimidin-2-Yl]Amino]-4-Methoxyphenyl]Prop-2-Enamide
CAS No.	2099058-35-0
Molecular Formula	C31H34N8O2S
Molecular Weight	582.72 g/mol
Synonyms	2099058-35-0; N-[2-[2-(Dimethylamino)ethyl(methyl)amino]-5-[[4-(1H-indol-3-yl)thieno[3,2-d]pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide; (E)-N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1H-indol-3-yl)thieno[3,2-d]pyrimidin-2-yl)amino)-4-methoxyphenyl)acrylamide; Acrylamide derivative kinase inhibitor intermediate; Thienopyrimidine-indole conjugate
EINECS	Contact for details

Quality Control

Our n-[2-[2-(Dimethylamino)Ethyl(Methyl)Amino]-5-[[4-(1H-Indol-3-Yl)Thieno[3,2-D]Pyrimidin-2-Yl]Amino]-4-Methoxyphenyl]Prop-2-Enamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.