Description

4',5'-Didehydro-2'-o-(2-Methoxyethyl)Uridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating next-generation nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Pro-drug Development: Employed in the design and synthesis of pro-drugs to enhance bioavailability and targeting of active pharmaceutical ingredients.
• Antiviral Agent Synthesis: Serves as a core scaffold for developing compounds targeting viral polymerases (e.g., for hepatitis or other viral infections).
• Labeled Compound Synthesis: Can be used to create isotopically labeled versions (e.g., with C-13, N-15) for metabolic tracing and pharmacokinetic studies.
• Medicinal Chemistry: Provides a versatile template for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.

Basic Information

Product Name	4',5'-Didehydro-2'-o-(2-Methoxyethyl)Uridine
CAS No.	2095417-78-8
Molecular Formula	C12H16N2O7
Molecular Weight	300.27 g/mol
Synonyms	2'-O-(2-Methoxyethyl)-4',5'-didehydrouridine; 2'-O-Methoxyethyl-4',5'-didehydrouridine; 4',5'-Didehydro-2'-O-(2-methoxyethyl)uridine; Uridine, 4',5'-didehydro-2'-O-(2-methoxyethyl)-; 2'-MOE-4',5'-didehydrouridine
EINECS	Contact for details

Quality Control

Our 4',5'-Didehydro-2'-o-(2-Methoxyethyl)Uridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay value, ensuring compliance with research and development grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.