Description

2'-Azido-2'-Deoxy-5-Methylcytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block and a versatile chemical probe for the development of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in nucleoside chemistry, prodrug design, and the study of nucleic acid metabolism.

Application

• Antiviral Drug Research: A key synthetic intermediate for the development of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral agents.
• Oncology Research: Investigated as a prodrug precursor for targeted cancer therapies, leveraging its modified structure for selective activation.
• Biochemical Probes: Used in click chemistry applications due to the reactive azido group, enabling labeling and study of nucleic acid interactions and cellular processes.
• Nucleoside Chemistry: Serves as a specialized monomer for the synthesis of oligonucleotides with unique properties for diagnostic and therapeutic applications.
• Enzyme Inhibition Studies: Employed to study the mechanism and inhibition of enzymes involved in nucleoside and nucleotide metabolism.

Basic Information

Product Name	2'-Azido-2'-Deoxy-5-Methylcytidine
CAS No.	2095417-75-5
Molecular Formula	C10H13N7O4
Molecular Weight	295.26 g/mol
Synonyms	5-Methyl-2'-azido-2'-deoxycytidine; 2'-Azido-5-methyl-2'-deoxycytidine; 2'-N3-5-Me-dC; 1-((2R,3S,5R)-3-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; Azidodeoxy-5-methylcytidine
EINECS	Contact for details

Quality Control

Our 2'-Azido-2'-Deoxy-5-Methylcytidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.