Description

1-[6-Phosphono-2-o-Methyl-β-D-Ribo-Hexofuranosyl]Uracil is a chemically modified nucleoside derivative, a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a precursor or intermediate in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery pipelines. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for cutting-edge medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel nucleoside analog drugs.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated as a precursor for antimetabolite drugs designed to inhibit cancer cell proliferation.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to probe biological pathways.
• Prodrug Development: Utilized in creating masked or activated forms of therapeutic nucleosides for improved delivery.
• Fine Chemical Synthesis: Acts as a specialized reagent for constructing complex, sugar-modified molecular architectures.

Basic Information

Item	Details
Product Name	1-[6-Phosphono-2-o-Methyl-β-D-Ribo-Hexofuranosyl]Uracil
CAS No.	2095417-68-6
Molecular Formula	C₁₂H₁₉N₂O₁₁P
Molecular Weight	398.26 g/mol
Synonyms	2'-O-Methyluridine 5'-monophosphate; 2'-O-Methyl-UMP; 1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil; Uridine, 2'-O-methyl-, 5'-(dihydrogen phosphate); 2'-OMe-UMP; 2'-Methoxyuridine 5'-phosphate; Modified nucleoside monophosphate
EINECS	Contact for details

Quality Control

Our production of 1-[6-Phosphono-2-o-Methyl-β-D-Ribo-Hexofuranosyl]Uracil adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. While produced under controlled conditions suitable for research use, specifications can be developed to meet specific project requirements. For cGMP-grade material or material manufactured under a Quality Agreement, please contact our regulatory affairs team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.