Description

2-Cyanomethylthioadenosine is a specialized nucleoside analog derivative with a unique cyanomethylthio modification at the ribose moiety. This compound is a critical building block and research chemical in advanced pharmaceutical development and biochemical studies. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutics and exploring enzymatic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel adenosine receptor modulators and antiviral/anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for methyltransferases and other nucleoside-processing enzymes.
• Proteomics & Molecular Biology: Employed in the development of activity-based probes (ABPs) for labeling and studying protein function.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Facilitates fundamental research in nucleotide metabolism and signal transduction pathways.

Basic Information

Product Name	2-Cyanomethylthioadenosine
CAS No.	2095417-67-5
Molecular Formula	C12H14N6O4S
Molecular Weight	338.35 g/mol
Synonyms	2-[(Cyanomethyl)thio]adenosine; 2-CMTA; Adenosine, 2-[(cyanomethyl)thio]-; 2-S-Cyanomethyladenosine; 2-Cyanomethylmercaptoadenosine; 2-(Cyanomethylthio)adenosine; 2-Cyanomethylsulfanyladenosine
EINECS	Contact for details

Quality Control

Our 2-Cyanomethylthioadenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.