Description

3'-Azido-3'-Deoxy-β-L-Cytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside reverse transcriptase inhibitors (NRTIs). It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for the synthesis of active pharmaceutical ingredients (APIs) and for biochemical studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral drugs, including potential treatments for HIV and hepatitis.
• Anticancer Agent Research: Used in the development and study of cytidine analogs designed to inhibit cancer cell proliferation.
• Biochemical Probe: Employed in molecular biology and enzymology studies to investigate nucleotide metabolism and enzyme mechanisms.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Serves as a critical raw material for scaling up the production of target therapeutic compounds under GMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery pathways.

Basic Information

Product Name	3'-Azido-3'-Deoxy-β-L-Cytidine
CAS No.	2095417-59-5
Molecular Formula	C9H12N6O4
Molecular Weight	268.23 g/mol
Synonyms	3'-Azido-3'-deoxy-L-cytidine; 3'-N3-L-Cytidine; 1-((2R,3S,5R)-3-Azido-5-(hydroxymethyl)oxolan-2-yl)-4-amino-1,2-dihydropyrimidin-2-one; β-L-3'-Azido-3'-deoxycytidine; L-3'-Azido-3'-deoxycytidine; L-N3C; Azidocytidine L-isomer
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-β-L-Cytidine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<10 ppm
Related Substances (HPLC)	Total impurities <2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.