Description

3'-Deoxy-5-Methoxyuridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for targeting viral polymerases and exploring mechanisms of nucleic acid metabolism. The product is supplied to the global market with a focus on high purity and reliable supply chain integrity.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate polymerase activity and nucleic acid synthesis pathways.
• Antiviral Agent Development: Serves as a core scaffold for creating analogs active against a range of DNA and RNA viruses.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of lead compounds.
• Labeled Compound Synthesis: Can be used as a starting material for the preparation of isotopically labeled (e.g., C13, N15, H3) versions for metabolic and tracer studies.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and molecular pharmacology.

Basic Information

Product Name	3'-Deoxy-5-Methoxyuridine
CAS No.	2095417-49-3
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methoxy-2'-deoxyuridine; 3'-Deoxy-5-methoxythymidine; 5-Methoxy-3'-deoxyuridine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 3'-d-5-Methoxyuridine
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-5-Methoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.