Description

2'-Deoxy-2'-Fluoro-3-Deaza-Arabinouridine is a chemically modified nucleoside analog, a key building block in medicinal chemistry and pharmaceutical research. This compound is valued for its role as a precursor in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular enzymes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate polymerase mechanisms and nucleotide metabolism.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Drug Development: Investigated for the creation of novel therapeutics against DNA and RNA viruses.
• Labeled Compound Synthesis: Can be used to prepare isotopically labeled versions for pharmacokinetic and metabolic tracing studies.
• Academic Research: Employed in university and institutional labs for fundamental studies in nucleic acid chemistry and biology.

Basic Information

Item	Detail
Product Name	2'-Deoxy-2'-Fluoro-3-Deaza-Arabinouridine
CAS No.	2095417-48-2
Molecular Formula	C11H14FN3O5
Molecular Weight	287.25 g/mol
Synonyms	2'-Deoxy-2'-fluoro-3-deaza-arabinouridine; 2'-Fluoro-2'-deoxy-3-deaza-arabinouridine; 3-Deaza-2'-deoxy-2'-fluoro-arabinouridine; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,3-diazin-2-one; 2'-F-3-Deaza-araU; F-3-Deaza-dAraU
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-3-Deaza-Arabinouridine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.