Description

5-Furan-2-Yl-2'-o-Methyl Uridine is a modified nucleoside building block of significant interest in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of oligonucleotides and nucleotide analogs, enabling the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of modified oligonucleotides used in therapeutic applications.
• Antisense & siRNA Research: Used in the development of gene-silencing drugs and research tools targeting specific mRNA sequences.
• Nucleic Acid Chemistry: Serves as a substrate for studying enzyme mechanisms or for creating labeled probes in molecular biology.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic properties of nucleotide analogs.
• Bioconjugation: The furan moiety can offer a handle for further chemical modifications or conjugation to delivery systems.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in oligonucleotide manufacturing.

Basic Information

Product Name	5-Furan-2-Yl-2'-o-Methyl Uridine
CAS No.	2095417-32-4
Molecular Formula	C15H16N2O7
Molecular Weight	336.30 g/mol
Synonyms	2'-O-Methyl-5-(2-furyl)uridine; 5-(2-Furyl)-2'-O-methyluridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl)-5-(furan-2-yl)pyrimidine-2,4-dione; 2'-O-Methyl-5-(2-furanyl)uridine; 5-(2-Furyl)-2'-O-methyl-uridine; Modified Uridine Nucleoside; Furan-modified Uridine Derivative
EINECS	Contact for details

Quality Control

Our production of 5-Furan-2-Yl-2'-o-Methyl Uridine adheres to stringent quality management protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with appropriate desiccant after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.