Description

4',5'-Didehydro-2'-o-(2-Methoxyethyl)-5-Methyluridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of novel therapeutic agents, particularly in the development of antiviral and anticancer nucleoside prodrugs. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in cutting-edge drug discovery and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Prodrug Development: Used in research to create modified nucleosides with enhanced bioavailability and targeted delivery.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Antiviral Agent Synthesis: A precursor in the development of potential therapeutics against RNA viruses.
• Labeled Compound Synthesis: Can be used to create isotopically labeled versions for metabolic tracing and pharmacokinetic studies.
• Oligonucleotide Modification: Employed to introduce specific modifications into synthetic oligonucleotides for research and diagnostic applications.

Basic Information

Item	Details
Product Name	4',5'-Didehydro-2'-o-(2-Methoxyethyl)-5-Methyluridine
CAS No.	2095417-31-3
Molecular Formula	C13H18N2O7
Molecular Weight	314.29 g/mol
Synonyms	2'-O-(2-Methoxyethyl)-5-methyl-4',5'-didehydrouridine; 5-Methyl-2'-O-(2-methoxyethyl)uridine 4',5'-didehydro derivative; 4',5'-Didehydro-5-methyl-2'-O-(2-methoxyethyl)uridine; 2'-MOE-5-methyl-4',5'-didehydrouridine; Modified 5-Methyluridine; Nucleoside analog 2095417-31-3
EINECS	Contact for details

Quality Control

Our 4',5'-Didehydro-2'-o-(2-Methoxyethyl)-5-Methyluridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.