Description

3'-Azido-3'-Deoxy-5-Fluorocytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its unique structural features, which include an azido group at the 3' position and a fluorine atom at the 5 position of the cytidine base, making it a crucial building block for probing biological mechanisms and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, nucleotide chemistry, and the synthesis of prodrugs or diagnostic probes.

Application

• Antiviral Research Intermediate: Serves as a key synthetic precursor in the development of novel nucleoside analog antiviral agents.
• Biochemical Probe Development: Used to study enzyme mechanisms, particularly those involving DNA/RNA polymerases and kinases, due to its modified sugar and base moieties.
• Medicinal Chemistry: A vital building block for constructing libraries of modified nucleotides for structure-activity relationship (SAR) studies.
• Prodrug Synthesis: Employed in the design and synthesis of prodrug candidates aimed at improving bioavailability and targeting.
• Click Chemistry Substrate: The azido group enables its use in bioorthogonal "click" chemistry reactions for labeling and conjugation applications in chemical biology.

Basic Information

Product Name	3'-Azido-3'-Deoxy-5-Fluorocytidine
CAS No.	2095417-18-6
Molecular Formula	C9H11FN6O4
Molecular Weight	286.23 g/mol
Synonyms	3'-Azido-3'-deoxy-5-fluorocytidine; 5-Fluoro-3'-azido-3'-deoxycytidine; 1-(3-Azido-3-deoxy-β-D-ribofuranosyl)-5-fluorocytosine; 3'-N3-5-F-dC; Azidodeoxyfluorocytidine; 3'-Azido-5-fluoro-3'-deoxycytidine; 3'-Azido-3'-deoxy-5-fluoro-cytidine
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-5-Fluorocytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.