Description

2-(4-Methylbenzyl)Thioadenosine is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a valuable biochemical tool for investigating nucleoside metabolism and designing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleotide-based drugs, antiviral research, and the study of enzyme mechanisms.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine deaminase, kinases, and other nucleoside-metabolizing enzymes.
• Proteomics & Molecular Biology: Employed in the study of RNA modification and as a tool compound for probing nucleic acid-protein interactions.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	2-(4-Methylbenzyl)Thioadenosine
CAS No.	2095417-16-4
Molecular Formula	C18H21N5O4S
Molecular Weight	403.46 g/mol
Synonyms	2-[(4-Methylphenyl)methyl]thioadenosine; 2-(p-Methylbenzyl)thioadenosine; 2-S-[(4-Methylphenyl)methyl]adenosine; Adenosine, 2-[(4-methylphenyl)methyl]thio-; 2-(4-Methylbenzyl)thio-adenosine; N6-(4-Methylbenzyl)adenosine derivative (related); 2-Substituted Thioadenosine Analog
EINECS	Contact for details

Quality Control

Our 2-(4-Methylbenzyl)Thioadenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.