Description

4',5'-Didehydro-2'-o-Methyl-5-Methyluridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound matters for its role as a critical intermediate in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery programs. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation nucleotide-based therapies and molecular probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a modified building block for studying nucleic acid structure, function, and enzyme interactions.
• Pro-drug Development: Serves as a key starting material for creating pro-drugs with enhanced bioavailability and targeted delivery.
• Antisense Oligonucleotide Synthesis: Incorporated into oligonucleotide chains to modulate stability, binding affinity, and biological activity.
• Diagnostic Probe Development: Utilized in the creation of labeled nucleotides for diagnostic assays and imaging techniques.
• Academic & Industrial R&D: Employed in exploratory chemistry for discovering new bioactive molecules and mechanisms.

Basic Information

Product Name	4',5'-Didehydro-2'-o-Methyl-5-Methyluridine
CAS No.	2095417-11-9
Molecular Formula	C12H14N2O6
Molecular Weight	282.25 g/mol
Synonyms	2'-O-Methyl-5-methyl-2',3'-didehydro-2',3'-dideoxyuridine; 5-Methyl-2'-O-methyl-2',3'-didehydro-2',3'-dideoxyuridine; 2'-O-Methyl-5-methyldidehydrodideoxyuridine; 4',5'-Didehydro-2'-O-methyl-5-methyluridine; Modified Nucleoside; Didehydro Nucleoside Analog
EINECS	Contact for details

Quality Control

Our 4',5'-Didehydro-2'-o-Methyl-5-Methyluridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.