Description

3'-Azido-3'-Deoxy-5-Methyl-β-L-Uridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel antiviral and anticancer agents, particularly within the field of nucleoside-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation treatments for viral infections and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analog prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of potential therapeutic agents targeting a range of viral pathogens.
• Oncology Research: Investigated as a precursor for compounds with potential anticancer activity.
• Biochemical Probe Development: Employed in the study of cellular processes and enzyme mechanisms due to its modified sugar moiety.
• Click Chemistry Substrate: The azido group makes it a valuable reactant for bioorthogonal conjugation and labeling applications.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	3'-Azido-3'-Deoxy-5-Methyl-β-L-Uridine
CAS No.	2095417-10-8
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	3'-Azido-3'-deoxy-5-methyl-β-L-uridine; 5-Methyl-3'-azido-3'-deoxy-β-L-uridine; 1-((2S,3S,4R,5R)-3-Azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methylpyrimidine-2,4-dione; β-L-3'-Azido-3'-deoxy-5-methyluridine; L-3'-Azido-3'-deoxy-5-methyluridine; 3'-N3-5-Me-L-Urd
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-5-Methyl-β-L-Uridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.