Description

1,N6-Etheno-Ara-Adenosine is a chemically modified nucleoside analog, specifically an etheno-bridged derivative of arabinosyladenosine. This compound is of significant interest in biochemical and pharmaceutical research due to its unique structure, which can impart altered biological activity and stability compared to its parent nucleosides. It serves as a critical intermediate and reference standard for scientists developing novel antiviral agents, anticancer therapeutics, and molecular probes. Researchers in medicinal chemistry, biochemistry, and pharmacology require this high-purity building block for drug discovery and mechanism-of-action studies.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies to investigate nucleotide metabolism and polymerase activity.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Employed in universities and research institutes for fundamental studies on nucleic acid chemistry and biology.
• Diagnostic Development: Potential use in the synthesis of labeled compounds for diagnostic assays and imaging agents.

Basic Information

Product Name	1,N6-Etheno-Ara-Adenosine
CAS No.	2095417-09-5
Molecular Formula	C₁₂H₁₄N₆O₄
Molecular Weight	306.28 g/mol
Synonyms	1,N6-Ethenoadenosine arabinoside; 1,N6-Etheno-9-β-D-arabinofuranosyladenine; Ara-1,N6-Ethenoadenosine; 9-β-D-Arabinofuranosyl-1,N6-ethenoadenine; 1,N6-ε-Adenosine arabinoside; Etheno-ara-A
EINECS	Contact for details

Quality Control

Our 1,N6-Etheno-Ara-Adenosine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.