Description

3'-Azido-3'-Deoxy-4-Deoyuridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular DNA/RNA metabolism. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs. The structural features of this azido-nucleoside make it a valuable probe and precursor for click chemistry applications and the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand polymerase mechanisms and nucleic acid metabolism.
• Probe Development: The azido functional group enables its use in bioorthogonal "click chemistry" for labeling, imaging, and target identification studies.
• Antiviral Agent Synthesis: Intermediate in the research and synthesis of potential therapeutic agents against a range of DNA and RNA viruses.
• Medicinal Chemistry: Building block for structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside analogs.
• Academic Research: Tool compound in universities and research institutes studying nucleic acid chemistry and drug design principles.

Basic Information

Product Name	3'-Azido-3'-Deoxy-4-Deoyuridine
CAS No.	2095417-07-3
Molecular Formula	C9H11N5O5
Molecular Weight	269.22 g/mol
Synonyms	3'-Azido-3'-deoxy-4'-deoxythymidine; 4'-Deoxy-3'-azidothymidine; AZT-4'-deoxy analog; 1-((2R,4S,5R)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-N3-4'-dT; 3'-Azido-4'-deoxythymidine
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-4-Deoyuridine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.