Description

5-Naphthyl--Methylaminocarbony-3'-o-Acetyl-2'-o-Methyluridine is a sophisticated, high-purity nucleoside derivative designed for advanced research and development applications. This compound is critical for scientists working on the synthesis and modification of oligonucleotides, where precise chemical structure is paramount. It serves as a key building block for researchers in pharmaceutical development, biotechnology, and life sciences, particularly in the creation of novel therapeutic agents and diagnostic probes.

Application

• Oligonucleotide Synthesis: A crucial phosphoramidite precursor for the solid-phase synthesis of modified RNA and DNA strands.
• Antisense & siRNA Therapeutics: Used in the development of chemically modified oligonucleotides for enhanced stability and target specificity in gene silencing applications.
• Bioconjugation & Probe Development: Acts as a reactive intermediate for attaching reporter molecules (e.g., fluorophores, biotin) to nucleic acids for diagnostic and imaging purposes.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in the search for new antiviral and anticancer nucleoside analogs.
• Academic & Industrial R&D: A valuable reagent for fundamental biochemical research exploring nucleic acid structure, function, and enzyme interactions.

Basic Information

Product Name	5-Naphthyl--Methylaminocarbony-3'-o-Acetyl-2'-o-Methyluridine
CAS No.	2095417-03-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-O-Methyl-3'-O-acetyl-5-(naphthylmethylaminocarbonyl)uridine; 5-[(Naphthalen-1-ylmethyl)carbamoyl]-2'-O-methyl-3'-O-acetyluridine; 3'-O-Acetyl-2'-O-methyl-5-(1-naphthylmethylaminocarbonyl)uridine; 5-(1-Naphthylmethylcarbamoyl)-2'-O-methyl-3'-O-acetyluridine; Modified Uridine Derivative CAS 2095417-03-9; Naphthyl-modified Uridine Phosphoramidite Precursor
EINECS	Contact for details

Quality Control

Our production of 5-Naphthyl--Methylaminocarbony-3'-o-Acetyl-2'-o-Methyluridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.