Description

(2-Amino-4-Bromo-5-Fluoro-Phenyl)-Methanol is a high-purity, multi-functional aromatic building block featuring amino, bromo, fluoro, and hydroxymethyl substituents. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where its unique halogen and functional group pattern enables precise structural modifications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific pharmacophores or create novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bromo and fluoro substituents for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functionalized surfaces where the amino and alcohol groups facilitate further chemical grafting.
• Fluorescent Dye and Sensor Precursor: The aromatic amine structure makes it a valuable intermediate for developing organic fluorescent probes and chemical sensors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aniline derivatives.

Basic Information

Product Name	(2-Amino-4-Bromo-5-Fluoro-Phenyl)-Methanol
CAS No.	2091283-08-6
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Amino-4-bromo-5-fluorobenzyl alcohol; 4-Bromo-5-fluoro-2-aminobenzyl alcohol; (2-Amino-4-bromo-5-fluorophenyl)methanol; 1-Amino-2-(hydroxymethyl)-4-bromo-5-fluorobenzene; Benzenemethanol, 2-amino-4-bromo-5-fluoro-; 2-(Hydroxymethyl)-4-bromo-5-fluoroaniline; 4-Bromo-5-fluoroanthranilyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-4-Bromo-5-Fluoro-Phenyl)-Methanol is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and commercial use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.