Description

M7(3'Omeg)(5')Pp-1-Imidazol CAS NO 2089461-53-8 is a specialized nucleoside analog derivative, a high-purity intermediate of significant value in advanced pharmaceutical research and development. This compound is critical for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in cutting-edge nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation antiviral and anticancer nucleotide prodrugs.
• Protease Inhibitor Research: Used in the development of targeted protease inhibitors for treating viral infections.
• Antisense Oligonucleotide (ASO) Synthesis: Serves as a modified monomer for creating therapeutic ASOs that modulate gene expression.
• Small Interfering RNA (siRNA) Development: Employed in the research and production of siRNA conjugates for RNA interference therapies.
• Bioconjugation & Probe Synthesis: Acts as a functional handle for creating labeled probes and bioconjugates used in diagnostic assays and cellular imaging.
• Medicinal Chemistry & SAR Studies: Essential for structure-activity relationship (SAR) studies to optimize drug potency and pharmacokinetic properties.

Basic Information

Product Name	M7(3'Omeg)(5')Pp-1-Imidazol
CAS No.	2089461-53-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-((2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)propyl 1H-imidazole-1-carboxylate; 3'-Deoxy-3'-fluoro-5'-O-(1H-imidazol-1-ylcarbonyl)adenosine; 3'-Fluoro-3'-deoxy-5'-O-(imidazolylcarbonyl)adenosine; 5'-O-(Imidazol-1-ylcarbonyl)-3'-deoxy-3'-fluoroadenosine; Nucleoside Phosphoramidite Intermediate; Adenosine Derivative M7; 3'-F-3'-dA-5'-Imidazolylcarboxylate
EINECS	Contact for details

Quality Control

Our M7(3'Omeg)(5')Pp-1-Imidazol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring material integrity for sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.