Description

(2-Amino-3-Chloro-5-Fluorophenyl)Methanol is a multifunctional aromatic building block featuring amino, chloro, fluoro, and hydroxymethyl substituents, making it a versatile intermediate for advanced synthesis. Its value lies in enabling precise molecular construction for high-value, complex organic molecules where regioselectivity and specific functional group compatibility are critical. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a core building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced polymers, dyes, and functional materials requiring specific halogenated and aminated aromatic structures.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	(2-Amino-3-Chloro-5-Fluorophenyl)Methanol
CAS No.	2089319-92-4
Molecular Formula	C7H7ClFNO
Molecular Weight	175.59 g/mol
Synonyms	2-Amino-3-chloro-5-fluorobenzyl alcohol; (3-Chloro-5-fluoro-2-aminophenyl)methanol; 1-(Aminomethyl)-2-chloro-4-fluorophenol; Benzenemethanol, 2-amino-3-chloro-5-fluoro-; 2-Amino-3-chloro-5-fluorobenzylalcohol; 3-Chloro-5-fluoro-2-aminobenzyl alcohol; 2-(Hydroxymethyl)-6-chloro-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our production of (2-Amino-3-Chloro-5-Fluorophenyl)Methanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ICH Q7 guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.