Description

(2S)-2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]-n-Methylpropanamide is a high-purity, synthetic iodinated aromatic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring multiple iodine atoms, makes it a critical intermediate for creating novel therapeutic agents, particularly in the fields of diagnostic imaging and targeted drug delivery. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel thyroid hormone analogs and receptor modulators.
• Diagnostic Agent Research: Serves as a core structure for developing radiolabeled (e.g., with I-123 or I-131) compounds used in medical imaging, such as SPECT agents.
• Biochemical Research: Used as a tool compound in studying protein-ligand interactions, enzyme inhibition, and cellular signaling pathways involving iodinated molecules.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce diiodophenoxy and diiodophenyl motifs into target molecules.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]-n-Methylpropanamide
CAS No.	2088032-52-2
Molecular Formula	C16H13I4N2O2
Molecular Weight	809.90 g/mol
Synonyms	N-Methyl-3,3',5,5'-Tetraiodothyronamine; T1AM; 3-Iodothyronamine Analog; (2S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide; Thyronamine Derivative; 3,5,3',5'-Tetraiodothyronamine; TIAM; CAS 2088032-52-2
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]-n-Methylpropanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.