Description

2'-Deoxy-2'-Fluoro-N3-(4-Nitrobenzyl)-β-D-Arabinouridine is a high-purity nucleoside analog derivative, specifically designed as a critical intermediate in advanced pharmaceutical synthesis. This compound matters because it provides a structurally precise building block for developing novel antiviral and anticancer therapeutics, enabling targeted research and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleic acid synthesis.
• Pro-drug Development: Serves as a protected intermediate for the synthesis of more complex, biologically active pro-drug molecules.
• Antiviral Agent Synthesis: Critical for the research and production of fluorinated arabinonucleoside-based therapeutic candidates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and selectivity of nucleoside drugs.
• Labeled Compound Synthesis: Can be used as a starting point for introducing radioactive or stable isotopes for tracer studies.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-N3-(4-Nitrobenzyl)-β-D-Arabinouridine
CAS No.	2072145-77-6
Molecular Formula	C16H16FN3O7
Molecular Weight	381.32 g/mol
Synonyms	2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-β-D-arabinouridine; 2'-Deoxy-2'-fluoro-N3-(p-nitrobenzyl)-β-D-arabinouridine; 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-[(4-nitrophenyl)methyl]pyrimidine-2,4-dione; N3-(4-Nitrobenzyl)-2'-deoxy-2'-fluoro-β-D-arabinouridine; 2'-F-araU-N3-Bn-NO2; FAU-N3-Bn-NO2 Intermediate
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-N3-(4-Nitrobenzyl)-β-D-Arabinouridine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.