Description

3'-Deoxy-3'-Fluoro-5-Methoxyluridine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for novel antiviral and anticancer therapeutics. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of modified nucleosides.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer drug candidates.
• Biochemical Research: Used as a probe or substrate in enzymatic studies to investigate nucleoside metabolism and polymerase activity.
• Antiviral Agent Development: Explored for its potential activity against a range of DNA and RNA viruses due to its modified sugar moiety.
• Oncology Research: Investigated for incorporation into DNA/RNA to inhibit tumor cell proliferation.
• Prodrug Synthesis: Acts as a precursor for the development of more bioavailable prodrug forms of therapeutic nucleosides.
• Labeled Compound Synthesis: Used in the preparation of isotopically labeled (e.g., 13C, 14C, 3H) versions for pharmacokinetic and metabolic studies.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-5-Methoxyluridine
CAS No.	2072145-76-5
Molecular Formula	C11H15FN2O6
Molecular Weight	290.25 g/mol
Synonyms	3'-Deoxy-3'-fluoro-5-methoxyuridine; 5-Methoxy-3'-deoxy-3'-fluorouridine; 1-((2R,4S,5R)-4-Fluoro-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-Fluoro-3'-deoxy-5-methoxyluridine; 3'-F-5-MeO-Urd; 3'-Fluoro-5-methoxy-2',3'-dideoxyuridine
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-5-Methoxyluridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.