Description

5-Iodo-2'-C-Methyl Cytidine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CROs/CMOs engaged in the synthesis of nucleoside-based prodrugs and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of next-generation antiviral agents, particularly targeting RNA viruses.
• Anticancer Drug Development: Used in research for creating nucleoside analogs that inhibit cancer cell proliferation.
• Prodrug Synthesis: Serves as a precursor for prodrug molecules designed to improve bioavailability and targeting.
• Biochemical Research: Utilized in studies of nucleoside metabolism, enzyme inhibition, and mechanism of action.
• Labeled Compound Synthesis: The iodine moiety allows for potential use in creating radiolabeled tracers for diagnostic imaging or metabolic studies.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.

Basic Information

Product Name	5-Iodo-2'-C-Methyl Cytidine
CAS No.	2072145-60-7
Molecular Formula	C10H13IN3O5
Molecular Weight	382.13 g/mol
Synonyms	5-Iodo-2'-C-methylcytidine; 2'-C-Methyl-5-iodocytidine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-2'-methylcytidine; 5-I-2'-C-Me-Cytidine
EINECS	Contact for details

Quality Control

Our 5-Iodo-2'-C-Methyl Cytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. The product is hygroscopic and should be handled in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.